主要研究经历:
1)主持国家重点研发计划项目“新机制和新功能植物生长调节剂创制与产业化”-课题《基于天然产物的植物生长调节剂创制》(2023YFD1700601, 2023/12-2027/12,409.80万元)
2)主持国家GG项目(密级)“免疫诱抗相关”子课题(NK202317040302,2023.10-2026.12,240万元)
3)主持江苏省产学研合作项目《基于植物和微生物次生代谢物的生物农药产品研发》(BY2022552,2022-2024,30万元)
4)主持江苏省农业自主创新项目《新型生物源除草剂戊羟咯草酮高活性手性分子的合成》(CX(21)3093, 2021/07-2023/06, 30万元)
5)主持中国农业大学植物生理学与生物化学国家重点实验室开放课题《链格孢菌诱导植物病害过程中的单线态氧信号与水杨酸信号交叉对话机制》(SKLPPBKF2118, 2021/01-2021/12, 10万元)
6)主持国家重点研发计划项目-课题《旱田生物除草剂新产品研制及产业化关键技术》(2017YFD0201304, 2017/07-2021/06,350万元)
7)主持中央高校基本科研业务费专项资金/重点项目《天然除草活性物质的筛选和作用机制的研究》(KYZ201530, 2015.1-2017.12, 20万元)
8)主持十二五863项目《植物生长调节剂、生物除草剂研究与产品创制》-子课题“生物除草剂丁羟咯酮研发” (2011AA10A206, 2011.1-2015.12, 50万元)
9)主持江苏省自然科学基金面上项目《紫茎泽兰致病型链格孢菌病原体侵染寄主的机制研究》(BK2012764, 2012.7-2015.6, 10万元)
10) 主持国家自然科学基金青年项目《紫茎泽兰致病型链格孢菌毒素AAC-toxin在病原体侵染寄主过程中的产生和作用》(31000834, 2011.1-2013.12, 20万元)
11) 主持教育部新教师博士点基金《紫茎泽兰致病型链格孢菌毒素(AAC-toxin)引起细胞死亡过程中活性氧的产生和作用》(200803071004, 2008.1-2010.12, 3.6万元)
12) 主持江苏省自然科学基金面上项目《紫茎泽兰致病型链格孢菌毒素AAC-toxin生物合成途径的研究》(BK2008338, 2008.7-2010.6, 7万元)
代表性论文和专利(*通讯作者)
1) Shi J, Wang H, Li M, Mi L, Gao Y, Qiang S, Zhang Y, Chen D, Dai X, Ma H, Lu H, Kim C*, Chen S*. Alternaria TeA toxin activates a chloroplast retrograde signaling pathway to facilitate JA-dependent pathogenicity. Plant Comm 2024, 5: 100775.
2) Yang Q, Guo Y, Wang H*, Luo Z, Chen Y, Jiang M, Lu H, Valverde BE, Qiang S, Strasser RJ, Chen S*, 2024. Action of the fungal compound citrinin, a bioherbicide candidate, on photosystem II. Pest Manag Sci 80: 133-148.
3) Guo Y, Li J, Shi J, Mi L, Han S, Liu W, Cheng D, Qiang S*, Kalaji HM, Chen S*, 2023. Griseofulvin inhibits root growth by targeting microtubule-associated proteins rather tubulins in Arabidopsis. Int J Mol Sci 2023, 24: 8692.
4) Shi J, Jiang M, Wang H, Luo Z, Guo Y, Chen Y, Zhao X, Qiang S, Strasser RJ, Kalaji HM, Chen S*, 2023. Effects of mycotoxin fumagillin, mevastatin, radicicol, and wortmannin on photosynthesis of Chlamydomonas reinhardtii. Plants 12: 665.
5) Yang Q, Guo Y, Li J, Wang L, Wang H, Liu G, Fang W, Qiang S, Strasser RJ, Chen S*, 2023. Natural plant inducer 2-amino-3-methylhexanoic acid protects physiological activity against high-temperature damage to tea (Camellia sinensis). Sci Hortic 312: 111836.
6) Jiang M, Yang Q, Wang H, Luo Z, Guo Y, Shi J, Wang X, Qiang S, Strasser RJ, Chen S*, 2022. Effect of mycotoxin cytochalasin A on photosystem II in Ageratina adenophora. Plants 11: 2797.
7) Wang H, Yao Q, Guo Y, Zhang Q, Wang Z, Strasser RJ, Valverde BE, Chen S*, Qiang S*, Kalaji HM, 2022. Structure-based ligand design and discovery of novel tenuazonic acid derivatives with high herbicidal activity. J Adv Res 40: 29-44.
8) Wang H, Li J, Yang Q, Wang L, Wang J, Zhang Y, Guo Y, Li R, Zhang R, Tao X, Valverde BE, Qiang S, Kalaji HM, Chen S*, 2022. Natural 2-amino-3-methylhexanoic acid as plant elicitor inducing resistance against temperature stress and pathogen attack. Int J Mol Sci 23: 5715.
9) Wang H, Guo Y, Luo Z, Gao L, Li R, Zhang Y, Kalaji HM, Qiang S, Chen S*, 2022. Recent advances in Alternaria phytotoxins: a review of their occurrence, structure, bioactivity and biosynthesis. J Fungi 8: 168. (Highly Cited)
10) Xiao W, Li J, Zhang Y, Guo Y, Fang W, Valverde BE, Yin J, Qiang S, Chen S*, 2022. A fungal Bipolaris bicolor strain as a potential bioherbicide for goosegrass (Eleusine indica) control. Pest Manag Sci 78: 1251-1264.
11) Guo Y, Liu W, Wang H, Wang X, Kalaji HM, Qiang S, Strasser RJ, Chen S*, 2021. Action mode of mycotoxin patulin as a novel natural photosystem II inhibitor. J Agric Food Chem 69: 7313-7323.
12) Shi J, Zhang M, Gao L, Yang Q, Kalaji HM, Qiang S, Strasser RJ, Chen S*, 2021. Tenuazonic acid-triggered cell death is the essential prerequisite for Alternaria alternata (Fr.) Keissler to infect successfully host Ageratina adenophora. Cells 10: 1010.
13) Guo Y, Lu Y, Goltsev V, Strasser RJ, Kalaji HM, Wang H, Wang X, Chen S*, Qiang S, 2020. Comparative effect of tenuazonic acid, diuron, bentazone, dibromothymoquinone and methyl viologen on the kinetics of Chl a fluorescence rise OJIP and the MR820 signal. Plant Physiol Biochem, 156: 39-48.
14) Guo Y, Cheng J, Lu Y, Wang H, Shi J, Gao Y, Yin C, Wang X, Chen S*, Strasser RJ and Qiang S, 2020. Novel action targets of natural product gliotoxin in photosynthetic apparatus. Front Plant Sci 10: 1688.
15) Xiao W, Wang H, Liu W, Wang X, Guo Y, Strasser RJ, Qiang S, Chen S*, Hu Z, 2020. Action of alamethicin in photosystem Ⅱ probed by the fast chlorophyll fluorescence rise kinetics and the JIP-test. Photosynthetica 58: 173-183.
16) Guo Y, Zhang Y, Lu Y, Shi J, Chen S*, Strasser RJ, Qiang S, Hu Z, 2020. Effect of AtLFNR1 deficiency on chlorophyll a fluorescence rise kinetics OJIP of Arabidopsis. Photosynthetica 58: 206-213.
17) Gao Y, Liu W, Wang X, Yang L, Han S, Chen S*, Strasser RJ, Valverde BE, Qiang S, 2018. Comparative phytotoxicity of usnic acid, salicylic acid, cinnamic acid and benzoic acid on photosynthetic apparatus of Chlamydomonas reinhardtii. Plant Physiol Biochem 128: 1-12.
18) Chen S, Qiang S*, 2017. Recent advances in tenuazonic acid as a potential herbicide. Pest Biochem Physiol 143(9): 252-257.
19) Chen S*, Yang J, Zhang M, Strasser RJ, Qiang S*, 2016. Classification and characteristics of heat tolerance in Ageratina adenophora populations using fast chlorophyll a fluorescence rise O-J-I-P. Environ Exp Bot 122: 126-140.
20) Chen S*, Kim C*, Lee J, Lee H, Fei Z, Wang L, Apel K*, 2015. Blocking the QB-binding site of photosystem II by tenuazonic acid, a non-host-specific toxin of Alternaria alternata, activates singlet oxygen-mediated and EXECUTER-dependent signaling in Arabidopsis. Plant Cell Environ 38: 1069-1080.
21) Chen S*, Kang Y, Zhang M, Wang X, Strasser RJ, Zhou B, Qiang S*, 2015. Differential sensitivity to the potential bioherbicide tenuazonic acid probed by the JIP-test based on fast chlorophyll fluorescence kinetics. Environ Exp Bot 112: 1-15.
22) Chen S*, Strasser RJ, Qiang S*, 2014. In vivo assessment of effect of phytotoxin tenuazonic acid on PSII reaction centers. Plant Physiol Biochem 84: 10-21.
23) Xiang M, Chen S*, 2013. Effect of vulculic acid produced by Nimbya alternantherae on the photosynthetic apparatus of Alternanthera philoxeroides. Plant Physiol Biochem 65(4): 81-88.
24) Chen S, Yin C, Strasser RJ, Govindjee, Yang C, Qiang S, 2012. Reactive oxygen species from chloroplasts contribute to 3-acetyl-5-isopropyltetramic acid -induced leaf necrosis of Arabidopsis thaliana. Plant Physiol Biochem 52: 38-51.
25) Chen S, Zhou F, Yin C, Strasser RJ, Qiang S, Yang C, 2011. Application of fast chlorophyll a fluorescence kinetics to probe action target of 3-acetyl-5-isopropyltetramic acid. Environ Exp Bot 71: 269-279.
26) Chen S, Ying C, Qiang S, Zhou F, Dai X, 2010. Chloroplastic oxidative burst induced by tenuazonic acid, a natural photosynthesis inhibitor, triggers cell necrosis in Eupatorium adenophorum Spreng. BBA-Bioenergetics 1797: 391-405.
27) Chen S, Yin C, Dai X, Qiang S, Xu X, 2008. Action of tenuazonic acid, a natural phytotoxin, on photosystem II of spinach. Environ Exp Bot 62: 279-289.
28) Chen S, Xu X, Dai X, Yang C, Qiang S, 2007. Identification of tenuazonic acid as a novel type of natural photosystem II inhibitor binding in QB-site of Chlamydomonas reinhardtii. BBA-Bioenergetics 1767: 306-318.
29) Chen S, Dai X, Qiang S, Tang Y, 2005. Effect of a nonhost-selective toxin from Alternaria alternata on chloroplast-electron transfer activity in Eupatorium adenophorum. Plant Phath 54: 671-677.
30) 高沥文, 陈世国*, 张裕, 强胜, 2022. 基于 RNA 干扰的生物农药的发展现状与展望. 中国生物防治学报 38: 700-715.
31) 张亚鑫, 肖婉, 张峥, 韦佳佳, 强胜, 陈世国*, 2021. 稻田稗属杂草致病菌的分离与鉴定. 中国生物防治学报 37: 1276-1287.
32) 陆俞萍, 肖婉, 房婉萍, 强胜, 陈世国*, 2021. 几种茶园杂草生防菌的分离鉴定. 中国生物防治学报 37: 564-574.
部分专利:
陈世国, 李晶晶, 汪岚, 王赫, 强胜, 房婉萍, 张裕. 2-氨基-3-甲基己酸在提高茶叶品质中的应用. 2022年4月20日, 中国发明专利,ZL202110795699.5
陈世国, 王赫, 谭伟明, 汪靖, 李晶晶, 房婉萍, 张裕, 强胜. 2-氨基-3-甲基己酸在促进植物生长和增产上的应用. 2022年3月2日,中国发明专利,ZL202110975196.6
陈世国, 肖婉, 强胜, 王赫, 房婉萍, 柳伟哲, 陆俞萍. 一种具有除草活性的双色平脐孺胞菌及其应用. 2021年11月12日, 中国发明专利,ZL202010166462.6
陈世国, 李晶晶, 汪岚, 王赫, 强胜, 房婉萍, 张裕. 2-氨基-3甲基己酸作为植物免疫诱抗剂的应用. 2021年8月13日, 中国发明专利,ZL202011549486.6
Qiang S, Chen SG, Yang CL, Dai XB, Dong YF. A technique for modification of a bio-product molecule and application of weed control. European Patent(欧洲), EP1997803 B1 (2018年2月)
强胜, 陈世国, 杨春龙, 戴新宾, 董云发.一种生物源化合物的分子修饰和用于除草的方法. 2017年11月, 中国, 专利号ZL201410175454.2
Qiang S, Chen SG, Yang CL, Dai XB, Dong YF. Method for eradicating weeds with derivatives of 3-acetyl-5-sec-butyl-4-hydroxy-3-pyrrolin-2-one. US Patent(美国), US9468209 B2 (2016年10月); US Patent (美国), US8921274 B2 (2014年12月)